Detalhe da pesquisa
1.
High Potency of a Bivalent Human VH Domain in SARS-CoV-2 Animal Models.
Cell
; 183(2): 429-441.e16, 2020 10 15.
Artigo
Inglês
| MEDLINE | ID: mdl-32941803
2.
Generation of a humanized mAce2 and a conditional hACE2 mouse models permissive to SARS-COV-2 infection.
Mamm Genome
; 2024 Mar 15.
Artigo
Inglês
| MEDLINE | ID: mdl-38488938
3.
Bepridil is potent against SARS-CoV-2 in vitro.
Proc Natl Acad Sci U S A
; 118(10)2021 03 09.
Artigo
Inglês
| MEDLINE | ID: mdl-33597253
4.
Novel virus-like nanoparticle vaccine effectively protects animal model from SARS-CoV-2 infection.
PLoS Pathog
; 17(9): e1009897, 2021 09.
Artigo
Inglês
| MEDLINE | ID: mdl-34492082
5.
Rapid identification of a human antibody with high prophylactic and therapeutic efficacy in three animal models of SARS-CoV-2 infection.
Proc Natl Acad Sci U S A
; 117(47): 29832-29838, 2020 11 24.
Artigo
Inglês
| MEDLINE | ID: mdl-33139569
6.
Increased talin-vinculin spatial proximities in livers in response to spotted fever group rickettsial and Ebola virus infections.
Lab Invest
; 100(8): 1030-1041, 2020 08.
Artigo
Inglês
| MEDLINE | ID: mdl-32238906
7.
A new role for host annexin A2 in establishing bacterial adhesion to vascular endothelial cells: lines of evidence from atomic force microscopy and an in vivo study.
Lab Invest
; 99(11): 1650-1660, 2019 11.
Artigo
Inglês
| MEDLINE | ID: mdl-31253864
8.
An orally bioavailable SARS-CoV-2 main protease inhibitor exhibits improved affinity and reduced sensitivity to mutations.
Sci Transl Med
; 16(738): eadi0979, 2024 Mar 13.
Artigo
Inglês
| MEDLINE | ID: mdl-38478629
9.
Circulating Reelin promotes inflammation and modulates disease activity in acute and long COVID-19 cases.
Front Immunol
; 14: 1185748, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-37441066
10.
Protective Efficacy of Novel Engineered Human ACE2-Fc Fusion Protein Against Pan-SARS-CoV-2 Infection In Vitro and in Vivo.
J Med Chem
; 66(24): 16646-16657, 2023 12 28.
Artigo
Inglês
| MEDLINE | ID: mdl-38100534
11.
Self-Masked Aldehyde Inhibitors of Human Cathepsin L Are Potent Anti-CoV-2 Agents.
Front Chem
; 10: 867928, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-35860632
12.
Deciphering COVID-19 host transcriptomic complexity and variations for therapeutic discovery against new variants.
iScience
; 25(10): 105068, 2022 Oct 21.
Artigo
Inglês
| MEDLINE | ID: mdl-36093376
13.
A Bacteriophage-Based, Highly Efficacious, Needle- and Adjuvant-Free, Mucosal COVID-19 Vaccine.
mBio
; 13(4): e0182222, 2022 08 30.
Artigo
Inglês
| MEDLINE | ID: mdl-35900097
14.
Potent Anti-SARS-CoV-2 Activity by the Natural Product Gallinamide A and Analogues via Inhibition of Cathepsin L.
J Med Chem
; 65(4): 2956-2970, 2022 02 24.
Artigo
Inglês
| MEDLINE | ID: mdl-34730959
15.
Comparison of replicating and nonreplicating vaccines against SARS-CoV-2.
Sci Adv
; 8(34): eabm8563, 2022 Aug 26.
Artigo
Inglês
| MEDLINE | ID: mdl-36001674
16.
Broad ultra-potent neutralization of SARS-CoV-2 variants by monoclonal antibodies specific to the tip of RBD.
Cell Discov
; 8(1): 16, 2022 Feb 15.
Artigo
Inglês
| MEDLINE | ID: mdl-35169121
17.
Discovery of Highly Potent Fusion Inhibitors with Potential Pan-Coronavirus Activity That Effectively Inhibit Major COVID-19 Variants of Concern (VOCs) in Pseudovirus-Based Assays.
Viruses
; 14(1)2021 12 31.
Artigo
Inglês
| MEDLINE | ID: mdl-35062273
18.
A universal bacteriophage T4 nanoparticle platform to design multiplex SARS-CoV-2 vaccine candidates by CRISPR engineering.
Sci Adv
; 7(37): eabh1547, 2021 Sep 10.
Artigo
Inglês
| MEDLINE | ID: mdl-34516878
19.
A Universal Bacteriophage T4 Nanoparticle Platform to Design Multiplex SARS-CoV-2 Vaccine Candidates by CRISPR Engineering.
bioRxiv
; 2021 Jan 20.
Artigo
Inglês
| MEDLINE | ID: mdl-33501450
20.
A Quick Route to Multiple Highly Potent SARS-CoV-2 Main Protease Inhibitors*.
ChemMedChem
; 16(6): 942-948, 2021 03 18.
Artigo
Inglês
| MEDLINE | ID: mdl-33283984